ChemicalBook > CAS DataBase List > (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

Product Name
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
CAS No.
80751-65-1
Chemical Name
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
Synonyms
Cl-apb;Chloro-AP;SK&F 82958;SKF82958 HBr;SKF82958,SKF 82958;6H-Benzo[cd]pyren-7-one;(±)-SKF 82958;CHLORO-APB;(+/-)-SKF-82958 HYDROBROMIDE;(+/-)-Chloro-apbhydrobromide;(+/-)-CHLORO-APB HYDROBROMIDE
CBNumber
CB3251102
Molecular Formula
C19H20ClNO2
Formula Weight
329.82
MOL File
80751-65-1.mol
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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Property

Boiling point:
473.7±45.0 °C(Predicted)
Density 
1.234±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: 3.7 mg/mL
form 
solid
pka
8.73±0.40(Predicted)
color 
tan
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C130
Product name
Chloro-APB hydrobromide
Purity
solid
Packaging
5mg
Price
$178
Updated
2024/03/01
Sigma-Aldrich
Product number
C130
Product name
Chloro-APB hydrobromide
Purity
solid
Packaging
25mg
Price
$244.4
Updated
2024/03/01
Sigma-Aldrich
Product number
C130
Product name
Chloro-APB hydrobromide
Purity
solid
Packaging
100mg
Price
$2010
Updated
2023/01/07
TRC
Product number
C364438
Product name
Chloro-APB hydrobromide
Packaging
10mg
Price
$180
Updated
2021/12/16
Usbiological
Product number
466156
Product name
SKF 82958 Hydrobromide
Packaging
5mg
Price
$355
Updated
2021/12/16
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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties,Usage,Production

Uses

Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice.

Definition

ChEBI: 9-chloro-5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol is a benzazepine.

Biochem/physiol Actions

Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats.

(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Suppliers

China 19 Switzerland 1 Ukraine 1 United Kingdom 1 United States 7 Global 29
Musechem
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info@musechem.com
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marketing@targetmol.com
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BOC Sciences
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80751-65-1, (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDERelated Search:

2-(3-Chlorophenyl)ethylamine 3-CHLOROCATECHOL Dopamine 3-CHLORO-5-METHYLPHENOL 3-CHLORO-4-METHYLPHENOL Hordenine hydrochloride N,N-BIS(2-PHENYL-ETHYL)-N-METHYL-AMINE 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-OL N,beta-Dimethylphenethylamine hydrochloride [2-(3-CHLORO-PHENYL)-ETHYL]-ETHYL-AMINE 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE N-ISOBUTYL-2-PROPEN-1-AMINE 6-CHLORO-2,3,4,5-TETRAHYDRO-1-(3-METHYLPHENYL)-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE [2-(3-CHLORO-PHENYL)-ETHYL]-METHYL-AMINE ethyl(1-phenylethyl)benzene

  • (±)-SKF 82958;CHLORO-APB
  • (+/-)-SKF-82958 HYDROBROMIDE
  • (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
  • 6-CHLORO-N-ALLYL-SKF-38393 HYDROBROMIDE
  • SK&F 82958
  • (±)-SKF-82958 hydrobromide, 6-Chloro-N-allyl-SKF-38393 hydrobromide, (±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
  • 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol
  • 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-
  • 6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
  • Cl-apb
  • SKF82958 HBr
  • 3-allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
  • (+/-)-CHLORO-APB HYDROBROMIDE
  • (+/-)-CHLORO-APB HYDROBROMIDE ((+/-)-SKF -82958 HBR)
  • 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-
  • (+/-)-Chloro-apbhydrobromide
  • Chloro-AP
  • 6H-Benzo[cd]pyren-7-one
  • (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
  • SKF82958,SKF 82958
  • 80751-65-1
  • C19H20ClNO2HBr